1. Immuno-therapeutic treatment of cancer – The patent pending Entest application involves perfecting the use of cell lines for sustained release of immunologically relevant cytokines for maximum anti-tumor immune responses in treating cancer. The treatment process itself will utilize an implantable encapsulation device as the vaccine delivery system and the initial focus will be treatment of cancer in canines. The Company’s initial goal is to treat 2,000 dogs at $3,000 per dog (yielding $6,000,000 in revenue) and believes revenue could begin to be generated within the next 9 months. This canine cancer treatment may also provide clinical support for expansion into human cancer treatment.
2. Entest has applied for a contract with the National Cancer Institute (NCI) for the initial development of an immuno-therapeutic cancer drug. This contract, if awarded to Entest, will have a value of $200,000 and will cover Phase I clinical evaluation. If the drug demonstrates reasonable efficacy, NCI may coordinate and fund further development through Phases II and III, with the ultimate goal being commercialization of the drug in partnership with NCI.
3. COPD –There is currently no cure for COPD and therapy is limited to management of the condition and its symptoms. Over the next 5 years, it is estimated that over $170 billion will be spent on treating COPD in the United States. Entest believes its COPD treatment, which utilizes patent pending adult stem cell therapy coupled with photoceutical device enhancement, has the potential to reverse COPD related lung damage as well as alleviate symptoms. The Company foresees substantial revenue in treating COPD and is currently in discussions with several entities regarding possible joint ventures involving the Company’s developing patent pending treatment.
Entest anticipates funding a significant amount of its research development costs by obtaining grant funding. The Company is in the process of applying for $3 million of federal grant funding for both COPD treatment and immuno-therapeutic treatment of cancer.